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How CBD Works in Your Body

Adam Wenguer

 

The world of cannabis culture and consumption has changed drastically over the years.   Since the 20th century, the narrative of cannabis has evolved from a drug that is associated  with psychosis and sin to a wellness adjunct that can improve life quality; and for good  reason. Since the discovery of the endocannabinoid system (ECS) in the 1940s, more and  more research — both observational and outcomes-based — has come to the surface,  leading us to conclude that the ECS, and associated cannabinoids, are of paramount  importance when considering human health.  

Before diving into how CBD works in the body, it is important we understand under what  context and through what vehicle it has its effects. The ECS is a lipid signaling system found  in all vertebrates and plays an essential role in immune and nervous system regulation  through a complex network of molecules and receptors. The two primary players in this  system are the receptors CB1 and CB2, which are found throughout the body. This receptor  system assists and maintains the regulation of several physiological processes such as  memory, appetite, sexual drive, blood pressure, pain sensation,  inflammation, and immunity. As mentioned above, CBD is one amongst hundreds of cannabinoids that  interact with the ECS to elicit various changes in your body’s physiology and overall  homeostatic balance. Clearly, the ECS is a paramount player in establishing overall wellness  and health, but how does CBD play into this beautiful and complex orchestration?  

CBD came to clinical interest once it’s anti-epileptic qualities and treatment for movement  disorders became established in the 1940s. Since that time, CBD is the second-most  studied plant-based cannabinoid next to THC. CBD is known for its anti-oxidative, anti-inflammatory, pain-relieving, and anxiety-reducing qualities, and thus a renewed  interest in CBD has come to the general public and to those seeking improved health.  Additionally, CBD is associated with reducing nausea and vomiting and increasing blood  flow and perfusion (Health Canada, 2018). Furthermore, CBD is non-psychoactive and does  not appear to bind to CB1 and CB2 receptors, or in other words, it does not get you “high”  as THC would.  

Taking a deeper dive into the bodily effects of CBD, what do we find? Without getting into  all the nitty-gritty science, essentially CBD reduces the binding strength and effect of the  CB1 receptor, resulting in the suppression and reduced release of several  neurotransmitters in the body. This has led researchers to believe that CBD could be play a  key role in treating both anxiety and insomnia, amongst the other benefits mentioned  above (Scherma, et al. 2008). In regards to emotional-wellness, CBD plays a key role in  serotonin production. And as if that wasn’t enough, CBD even plays a role in metabolism  and energy through calcium homeostasis in the mitochondria.  

It is clear that the many ways in which CBD affects one’s body are only outnumbered by the  library list of potential benefits to treat a multitude of ailments, conditions, and diseases.  From this, we can say that more research and study are needed in order to better  understand the therapeutic benefits of CBD. At Element Health we not only strive to  produce the highest quality CBD products but are also are invested in informing our  customers and community with the latest research and scientific findings. We believe in  providing you clarity and transparency through knowledge as a means to make your own  well-informed decisions.  

 

References

Scherma, Maria, et al. “The Endogenous Cannabinoid Anandamide Has Effects on Motivation and Anxiety That Are Revealed by Fatty Acid Amide Hydrolase (FAAH) Inhibition.”

Neuropharmacology , vol. 54, no. 1, 2008, pp. 129–140., doi:10.1016/j.neuropharm.2007.08.011.

Canada, Health. “Government of Canada.” For Health Care Professionals: Cannabis and

Cannabinoids - Canada.ca, Government of Canada, 12 Oct. 2018,

www.canada.ca/en/health-canada/services/drugs-medication/cannabis/information-medical-practitioners/information-health-care-professionals-cannabis-cannabinoids.html.

 


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